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All mammals have an endocannabinoid system (ECS). The ECS is involved in almost every system in you and your pet’s body. – cardiovascular, digestion, relaxation, and even the cognitive and memory functions.  The ECS is also a key factor in the mammalian body’s anti-inflammatory efforts. The ECS is controlled by receptors, which scientists call the CB1 and CB2 receptors.

CBD works directly with the ECS system by “antagonizing” the CB1 and CB2 receptors. CB1 receptors are one of the most abundant receptors in the brain and are found in almost every neuron in a mammal’s body. CB2 receptors are found almost exclusively in the immune system.

Cannabidiol (CBD) and related cannabinoids found in the hemp plant are the only compounds in the natural world that work with these receptors. According to scientists, this means that the mammalian body (yes, including all dogs and cats) have evolved to actually require CBD in order to function at our optimal levels of health.

Another important scientific find is that these receptors when activated by CBD, allow for two-way communication between a mammal’s various body systems. Previously, scientists thought the body’s signals went in one direction only. This two-way communication is what allows CBD to help your companion reach optimum levels of health.

Pet Releaf Usage and Serving Guide

Use this guide to find the suggested daily amount for your pet based on the exact Pet Releaf product, product strength, species, and weight range.

Product concentrations vary. Always match the product name and strength shown on your package before selecting an amount.

Ultra Releaf Oils

Ultra Releaf 100 oil (Dogs & Cats 1–25 lbs) - 100mg CBD per bottle

Ultra Releaf 100 oil (Dogs & Cats 1–25 lbs) - 100mg CBD per bottle suggested usage by pet weight
Pet Weight Suggested amount Approximate duration
Dogs 1–25 lbs 0.5 mL/day 60 days
Dogs 26–50 lbs 0.75 mL/day 40 days
Dogs 51–75 lbs 1 mL/day 30 days
Dogs 76–100 lbs 1.25 mL/day 24 days
Cats 1–15 lbs 0.25 mL/day 120 days
Cats Over 15 lbs 0.5 mL/day 60 days

Ultra Releaf 300 oil (Dogs 26–75 lbs) - 300mg CBD per bottle

Ultra Releaf 300 oil (Dogs 26–75 lbs) - 300mg CBD per bottle suggested usage by pet weight
Pet Weight Suggested amount Approximate duration
Dogs 26–50 lbs 0.25 mL/day 120 days
Dogs 51–75 lbs 0.5 mL/day 60 days
Dogs 76–100 lbs 0.75 mL/day 40 days
Dogs 101–150 lbs 1 full dropper/day 30 days
Dogs 150+ lbs 2 full droppers/day 15 days

Ultra Releaf 600 (Dogs 76+ lbs) - 600mg CBD per bottle

Ultra Releaf 600 (Dogs 76+ lbs) - 600mg CBD per bottle suggested usage by pet weight
Pet Weight Suggested amount Approximate duration
Dogs 26–50 lbs 0.25 mL/day 240 days
Dogs 51–75 lbs 0.5 mL/day 120 days
Dogs 76–100 lbs 0.75 mL/day 80 days
Dogs 101–150 lbs 1 full dropper/day 60 days
Dogs 150+ lbs 2 full droppers/day 30 days
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Stress Releaf Oils

150 Mini Stress Oil (For Dogs & Cats) - 150mg CBD per bottle

150 Mini Stress Oil (For Dogs & Cats) - 150mg CBD per bottle suggested usage by pet weight
Pet Weight Suggested amount Approximate duration
Dogs 1–25 lbs 0.75 mL/day Approximately 20 days
Dogs 26–50 lbs 1.5 mL/day Approximately 10 days
Dogs 51–75 lbs 2 mL/day Approximately 7.5 days
Dogs 76–100 lbs 2.75 mL/day Approximately 5.5 days
Cats 1–15 lbs 0.5 mL/day Approximately 30 days
Cats Over 15 lbs 1 mL/day Approximately 15 days

180 Feline Oil (For Cats) - 180mg CBD per bottle

180 Feline Oil (For Cats) - 180mg CBD per bottle suggested usage by pet weight
Pet Weight Suggested amount Approximate duration
Cats 3–5 lbs 0.25 mL/day Approximately 120 days
Cats 6–7 lbs 0.5 mL/day Approximately 60 days
Cats 8–10 lbs 0.75 mL/day Approximately 40 days
Cats 11–12 lbs 1 mL/day Approximately 30 days
Cats 13–15 lbs 1.25 mL/day Approximately 24 days
Cats 15+ lbs 1.5 mL/day Approximately 20 days

300 Stress Oil (Dogs & Cats 1–25 lbs) - 300mg CBD per bottle

300 Stress Oil (Dogs & Cats 1–25 lbs) - 300mg CBD per bottle suggested usage by pet weight
Pet Weight Suggested amount Approximate duration
Dogs 1–25 lbs 0.75 mL/day Approximately 40 days
Dogs 26–50 lbs 1.5 mL/day Approximately 20 days
Dogs 51–75 lbs 2 mL/day Approximately 15 days
Dogs 76–100 lbs 2.75 mL/day Approximately 11 days
Cats 1–15 lbs 0.5 mL/day Approximately 60 days
Cats Over 15 lbs 1 mL/day Approximately 30 days

600 Stress Oil (Dogs 26+ lbs) - 600mg CBD per bottle

600 Stress Oil (Dogs 26+ lbs) - 600mg CBD per bottle suggested usage by pet weight
Pet Weight Suggested amount Approximate duration
Dogs 26–50 lbs 0.5 mL/day Approximately 60 days
Dogs 51–75 lbs 1 mL/day Approximately 30 days
Dogs 76–100 lbs 1.5 mL/day Approximately 20 days
Dogs 101–150 lbs 2 mL/day Approximately 15 days
Dogs 150+ lbs 2.75 mL/day Approximately 11 days
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Hip & Joint Oils

300 Hip & Joint Oil (Dogs & Cats 1–25 lbs) - 300mg CBD per bottle

300 Hip & Joint Oil (Dogs & Cats 1–25 lbs) - 300mg CBD per bottle suggested usage by pet weight
Pet Weight Suggested amount Approximate duration
Dogs 1–25 lbs 0.75 mL/day Approximately 40 days
Dogs 26–50 lbs 1.5 mL/day Approximately 20 days
Dogs 51–75 lbs 2 mL/day Approximately 15 days
Dogs 76–100 lbs 2.75 mL/day Approximately 11 days
Cats 1–15 lbs 0.5 mL/day Approximately 60 days
Cats Over 15 lbs 1 mL/day Approximately 30 days

600 Hip & Joint oil (Dogs 26+ lbs) - 600mg CBD per bottle

600 Hip & Joint oil (Dogs 26+ lbs) - 600mg CBD per bottle suggested usage by pet weight
Pet Weight Suggested amount Approximate duration
Dogs 26–50 lbs 0.5 mL/day Approximately 60 days
Dogs 51–75 lbs 1 mL/day Approximately 30 days
Dogs 76–100 lbs 1.5 mL/day Approximately 20 days
Dogs 101–150 lbs 2 mL/day Approximately 15 days
Dogs 150+ lbs 2.75 mL/day Approximately 11 days
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Daily Releaf Oils

Daily Releaf 100 oil (Dogs & Cats 1–25 lbs) - 100mg CBD per bottle

Daily Releaf 100 oil (Dogs & Cats 1–25 lbs) - 100mg CBD per bottle suggested usage by pet weight
Pet Weight Suggested amount Approximate duration
Dogs 1–25 lbs 1.5 mL/day Approximately 20 days
Dogs 26–50 lbs 2.5 mL/day Approximately 12 days
Cats 1–15 lbs 1 mL/day Approximately 30 days
Cats Over 15 lbs 1.5 mL/day Approximately 20 days

Daily Releaf 200 oil (Dogs 26–50 lbs) - 200mg CBD per bottle

Daily Releaf 200 oil (Dogs 26–50 lbs) - 200mg CBD per bottle suggested usage by pet weight
Pet Weight Suggested amount Approximate duration
Dogs 1–25 lbs 0.75 mL/day Approximately 40 days
Dogs 26–50 lbs 1.5 mL/day Approximately 20 days
Dogs 51–75 lbs 2 mL/day Approximately 15 days
Dogs 76–100 lbs 2.5 mL/day Approximately 12 days

Daily Releaf 500 Oil (Dogs 51–75 lbs) - 500mg CBD per bottle

Daily Releaf 500 Oil (Dogs 51–75 lbs) - 500mg CBD per bottle suggested usage by pet weight
Pet Weight Suggested amount Approximate duration
Dogs 26–50 lbs 0.5 mL/day Approximately 60 days
Dogs 51–75 lbs 1 mL/day Approximately 30 days
Dogs 76–100 lbs 1.5 mL/day Approximately 20 days
Dogs 101–150 lbs 2 mL/day Approximately 15 days
Dogs 150+ lbs 2.75 mL/day Approximately 11 days

Daily Releaf 750 Oil (Dogs 76+ lbs) - 750mg CBD per bottle

Daily Releaf 750 Oil (Dogs 76+ lbs) - 750mg CBD per bottle suggested usage by pet weight
Pet Weight Suggested amount Approximate duration
Dogs 26–50 lbs 0.25–0.50 mL/day Approximately 60-120 days
Dogs 51–75 lbs 0.75 mL/day Approximately 40 days
Dogs 76–100 lbs 1 mL/day Approximately 30 days
Dogs 101–150 lbs 1.5 mL/day Approximately 20 days
Dogs 150+ lbs 2 mL/day Approximately 15 days
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Stress Bacon Edibites

Stress Bacon Travel size Edibites (3mg CBD per chew)

Stress Bacon Travel size Edibites (3mg CBD per chew) suggested usage by pet weight
Pet Weight Suggested amount Approximate duration
Dogs Up to 30 lbs 1–2 Edibites as needed Approximately 10 days
Dogs 31–60 lbs 2–3 Edibites as needed Approximately 5 days
Dogs 61–90 lbs 4–5 Edibites as needed Approximately 2 days

Stress Bacon Dog Edibites (3mg CBD per chew)

Stress Bacon Dog Edibites (3mg CBD per chew) suggested usage by pet weight
Pet Weight Suggested amount Approximate duration
Dogs Up to 30 lbs 1–2 Edibites as needed Approximately 30 days
Dogs 31–60 lbs 2–3 Edibites as needed Approximately 15 days
Dogs 61–90 lbs 4–5 Edibites as needed Approximately 6 days

Stress Bacon Large Dog Edibites (6mg CBD per chew)

Stress Bacon Large Dog Edibites (6mg CBD per chew) suggested usage by pet weight
Pet Weight Suggested amount Approximate duration
Dogs 40–50 lbs 1–2 Edibites as needed Approximately 30 days
Dogs 51–65 lbs 2–3 Edibites as needed Approximately 15 days
Dogs 66–100 lbs 3–4 Edibites as needed Approximately 10 days
Dogs 101–150 lbs 4–5 Edibites as needed Approximately 7 days

Stress Bacon Family Size Edibites (25+ lbs)

Stress Bacon Family Size Edibites (25+ lbs) suggested usage by pet weight
Pet Weight Suggested amount Approximate duration
Dogs Up to 20 lbs 0.5 Edibite per day Approximately 100 days
Dogs 21–40 lbs 1 Edibite as needed Approximately 50 days
Dogs 41–50 lbs 1–2 Edibites as needed Approximately 50 days
Dogs 51–65 lbs 2–3 Edibites as needed Approximately 25 days
Dogs 66–100 lbs 3–4 Edibites as needed Approximately 16 days
Dogs 101–150 lbs 4–5 Edibites as needed Approximately 7 days
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Hip & Joint Edibites

Hip & Joint Travel size Edibites (3mg CBD per chew)

Hip & Joint Travel size Edibites (3mg CBD per chew) suggested usage by pet weight
Pet Weight Suggested amount Approximate duration
Dogs Up to 30 lbs 1–2 Edibites as needed Approximately 10 days
Dogs 31–60 lbs 2–3 Edibites as needed Approximately 5 days
Dogs 61–90 lbs 4–5 Edibites as needed Approximately 2 days

Hip & Joint Small Dog Edibites (3mg CBD per chew)

Hip & Joint Small Dog Edibites (3mg CBD per chew) suggested usage by pet weight
Pet Weight Suggested amount Approximate duration
Dogs Up to 30 lbs 1–2 Edibites as needed Approximately 30 days
Dogs 31–60 lbs 2–3 Edibites as needed Approximately 15 days
Dogs 61–90 lbs 4–5 Edibites as needed Approximately 6 days

Hip & Joint Large Dog Edibites (6mg CBD per chew)

Hip & Joint Large Dog Edibites (6mg CBD per chew) suggested usage by pet weight
Pet Weight Suggested amount Approximate duration
Dogs 40–50 lbs 1–2 Edibites as needed Approximately 30 days
Dogs 51–65 lbs 2–3 Edibites as needed Approximately 15 days
Dogs 66–100 lbs 3–4 Edibites as needed Approximately 10 days
Dogs 101–150 lbs 4–5 Edibites as needed Approximately 7 days

Hip & Joint Family Size Edibites (25+ lbs)

Hip & Joint Family Size Edibites (25+ lbs) suggested usage by pet weight
Pet Weight Suggested amount Approximate duration
Dogs Up to 20 lbs 0.5 Edibite per day Approximately 100 days
Dogs 21–40 lbs 1 Edibite as needed Approximately 50 days
Dogs 41–50 lbs 1–2 Edibites as needed Approximately 50 days
Dogs 51–65 lbs 2–3 Edibites as needed Approximately 25 days
Dogs 66–100 lbs 3–4 Edibites as needed Approximately 16 days
Dogs 101–150 lbs 4–5 Edibites as needed Approximately 7 days
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Stress Peanut Butter Carob Edibites

Stress Peanut Butter Carob Travel size Edibites (3mg CBD per chew)

Stress Peanut Butter Carob Travel size Edibites (3mg CBD per chew) suggested usage by pet weight
Pet Weight Suggested amount Approximate duration
Dogs Up to 30 lbs 1–2 Edibites as needed Approximately 10 days
Dogs 31–60 lbs 2–3 Edibites as needed Approximately 5 days
Dogs 61–90 lbs 4–5 Edibites as needed Approximately 2 days

Stress Peanut Butter Carob Small Dog Edibites (3mg CBD per chew)

Stress Peanut Butter Carob Small Dog Edibites (3mg CBD per chew) suggested usage by pet weight
Pet Weight Suggested amount Approximate duration
Dogs Up to 30 lbs 1–2 Edibites as needed Approximately 30 days
Dogs 31–60 lbs 2–3 Edibites as needed Approximately 15 days
Dogs 61–90 lbs 4–5 Edibites as needed Approximately 6 days

Stress Peanut Butter Carob Large Dog Edibites (6mg CBD per chew)

Stress Peanut Butter Carob Large Dog Edibites (6mg CBD per chew) suggested usage by pet weight
Pet Weight Suggested amount Approximate duration
Dogs 40–50 lbs 1–2 Edibites as needed Approximately 30 days
Dogs 51–65 lbs 2–3 Edibites as needed Approximately 15 days
Dogs 66–100 lbs 3–4 Edibites as needed Approximately 10 days
Dogs 101–150 lbs 4–5 Edibites as needed Approximately 7 days

Stress Peanut Butter Carob Family Size Edibites (25+ lbs)

Stress Peanut Butter Carob Family Size Edibites (25+ lbs) suggested usage by pet weight
Pet Weight Suggested amount Approximate duration
Dogs Up to 20 lbs 0.5 Edibite per day Approximately 100 days
Dogs 21–40 lbs 1 Edibite as needed Approximately 50 days
Dogs 41–50 lbs 1–2 Edibites as needed Approximately 50 days
Dogs 51–65 lbs 2–3 Edibites as needed Approximately 25 days
Dogs 66–100 lbs 3–4 Edibites as needed Approximately 16 days
Dogs 101–150 lbs 4–5 Edibites as needed Approximately 7 days
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Daily Releaf Blueberry Cranberry Edibites

Daily Releaf Blueberry Cranberry Small Dog Edibites (3mg CBD per chew)

Daily Releaf Blueberry Cranberry Small Dog Edibites (3mg CBD per chew) suggested usage by pet weight
Pet Weight Suggested amount Approximate duration
Dogs Up to 30 lbs 1–2 Edibites as needed Approximately 30 days
Dogs 31–60 lbs 2–3 Edibites as needed Approximately 15 days
Dogs 61–90 lbs 4–5 Edibites as needed Approximately 6 days

Daily Releaf Blueberry Cranberry Large Dog Edibites (6mg CBD per chew)

Daily Releaf Blueberry Cranberry Large Dog Edibites (6mg CBD per chew) suggested usage by pet weight
Pet Weight Suggested amount Approximate duration
Dogs 40–50 lbs 1–2 Edibites as needed Approximately 30 days
Dogs 51–65 lbs 2–3 Edibites as needed Approximately 15 days
Dogs 66–100 lbs 3–4 Edibites as needed Approximately 10 days
Dogs 101–150 lbs 4–5 Edibites as needed Approximately 7 days
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Digestive Releaf Sweet Potato Edibites

Digestive Releaf Sweet Potato Small Dog Edibites (3mg CBD per chew)

Digestive Releaf Sweet Potato Small Dog Edibites (3mg CBD per chew) suggested usage by pet weight
Pet Weight Suggested amount Approximate duration
Dogs Up to 30 lbs 1–2 Edibites as needed Approximately 30 days
Dogs 31–60 lbs 2–3 Edibites as needed Approximately 15 days
Dogs 61–90 lbs 4–5 Edibites as needed Approximately 6 days

Digestive Releaf Sweet Potato Large Dog Edibites (6mg CBD per chew)

Digestive Releaf Sweet Potato Large Dog Edibites (6mg CBD per chew) suggested usage by pet weight
Pet Weight Suggested amount Approximate duration
Dogs 40–50 lbs 1–2 Edibites as needed Approximately 30 days
Dogs 51–65 lbs 2–3 Edibites as needed Approximately 15 days
Dogs 66–100 lbs 3–4 Edibites as needed Approximately 10 days
Dogs 101–150 lbs 4–5 Edibites as needed Approximately 7 days
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Sentesa

Sentesa Capsules: - 30mg CBD per capsule

Sentesa Capsules: - 30mg CBD per capsule suggested usage by pet weight
Pet Weight Suggested amount Approximate duration
Dogs 25+ lbs 2 capsules per day —
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Need help choosing a product or amount?

Contact the Pet Releaf customer experience team with your pet's species, weight, product name, and product strength so we can help you locate the correct guide.